Recombinant CD105 Monoclonal Antibody

• Background:

  This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  CD105

• UniProt:

  P17813

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human CD105 protein

• Target:

  HHT; RP11 228B; Osler Rendu Weber syndrome; END; HHT1; ORW1; CD105; ENG; endoglin; AI528660; AI662476; CD 105; CD105 antigen; EGLN; FLJ41744; ORW; Osler Rendu Weber syndrome 1; RP11 228B15.2; S-endoglin; SN6; AI528660; AI662476; CD 105; CD105; CD105 antigen; EGLN; END; Endoglin; Eng; FLJ41744; HHT1; ORW; ORW1; Osler Rendu Weber syndrome 1; RP11 228B15.2; S-endoglin; SN6; ENG; END; CD105 (Endoglin)

• Clonality:

  Monoclonal, Recombinant

• Clone:

  6G14

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Immunology; Stem Cells; Cancer; Cardiovascular

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:100-200; WB 1:1000-5000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  70 kDa

• Observed Molecular Weight:

  95 kDa

• Isotype:

  IgG, κ