Recombinant Cytokeratin 8 Monoclonal Antibody

• Background:

  KRT8 (keratin 8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

• Abbreviation:

  Cytokeratin 8

• UniProt:

  P05787

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human Cytokeratin 8 protein

• Target:

  CYK; KRT; CYK8; KRT8; CARD2; CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; K2C8; K8; Keratin 8; Keratin type II cytoskeletal 8; Keratin; type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8; CK 8; CK8; CK-8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; Keratin; Keratin 8; Keratin type II cytoskeletal 8; Keratin-8; Krt 2.8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; type II cytoskeletal 8; Type-II keratin Kb8

• Clonality:

  Monoclonal, Recombinant

• Clone:

  6F6

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Signal Transduction; Cancer

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000; WB 1:1000-1:5000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  54 kDa

• Observed Molecular Weight:

  54 kDa

• Isotype:

  IgG, κ