Recombinant RUNX1 Monoclonal Antibody

• Background:

  Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.

• Abbreviation:

  RUNX1

• UniProt:

  Q01196

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human RUNX1 protein

• Target:

  EVI; AML; RUNX; CBFA; AMLCR; AML1-EVI; RUNX1; AML1; AML1-EVI-1; AMLCR1; CBF2alpha; CBFA2; EVI-1; PEBP2aB; PEBP2alpha; Acute myeloid leukemia 3 protein; CBFA1; CBF-alpha-1; CCD1; CCDAML3; CLCD; ML3; oncogene AML-3; OSF2; OSF-2; PEA2aA; PEA2-alpha A; PEBP2aA; PEBP2-alpha A; RUNX2

• Clonality:

  Monoclonal, Recombinant

• Clone:

  6A10

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Neuroscience; Epigenetics and Nuclear Signaling; Stem Cells; Cancer; Developmental Biology

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  49 kDa

• Observed Molecular Weight:

  43-55 kDa

• Isotype:

  IgG, κ