Recombinant Phospho-SMAD5 (Ser463, Ser465) Monoclonal Antibody

• Background:

  The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

• Abbreviation:

  Smad5

• UniProt:

  Q99717

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  A synthetic peptide corresponding to residues around (Ser463, Ser465) of Human Phospho-SMAD5

• Target:

  JV5; MADH; SMAD; DWFC; JV5-1; MADH5; SMAD5

• Clonality:

  Monoclonal, Recombinant

• Clone:

  9F5

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Signal Transduction; Epigenetics and Nuclear Signaling; Stem Cells; Developmental Biology; Cancer; Kits; Lysates; Other; Metabolism

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  52 kDa

• Observed Molecular Weight:

  60 kDa

• Isotype:

  IgG, κ