Recombinant Cathepsin D/CTSD Monoclonal Antibody

• Background:

  This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

• Abbreviation:

  CTSD

• UniProt:

  P07339

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Cathepsin D/CTSD protein

• Target:

  CLN; CLN10; CPSD; HEL-S-130P; Cathepsin D; CTSD

• Clonality:

  Monoclonal

• Clone:

  3G8

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-P

• Field of Research:

  Neuroscience; Signal Transduction; Cancer; Cell Biology

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC-P 1:100-1:500

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  45 kDa

• Observed Molecular Weight:

  31 kDa

• Isotype:

  IgG