Recombinant CD32b/FCGR2B Monoclonal Antibody

• Background:

  Fc gamma RII, also known as CD32, is a group of three closely related proteins (Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIC) that share greater than 94% amino acid identity in their extracellular domains with Fc gamma RIIB and Fc gamma RIIC having identical extracellular domains. They function as transmembrane receptors for the Fc portion of IgG molecules. These proteins are expressed by various hematopoietic cells including monocytes, macrophages, neutrophils, NK, T and B cells. The Fc gamma RII proteins are involved in phagocytosis of immune complexes and modulation of antibody production by B cells.

• Abbreviation:

  FCGR2B

• UniProt:

  P31994

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant Human CD32b protein

• Target:

  FCG; CDw; Fcgr; IGFR; FCGR2B; CD32; CD32B; FCG2; FCGR2; IGFR2; CDw32; Fc-gamma-RIIb; FcRII-b; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; Fc-gamma RII-b; CD32 antigen; Fc fragment of IgG; Fc gamma receptor IIB; Fc gamma RII; Fc gamma RIIB; FCG2B; Fc-gamma RII; FCRII; FcγRII; IgG Fc receptor II beta; low affinity II; low affinity IIb; Low affinity immunoglobulin gamma Fc region receptor II; Ly-17; Lym 1; Lymphocyte antigen 17; receptor; receptor (CD32) ; receptor for; receptor for (CD32)

• Clonality:

  Monoclonal

• Clone:

  7F12

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-P

• Field of Research:

  Immunology; Stem Cells

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IHC-P 1:2500-1:15000

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  34 kDa

• Observed Molecular Weight:

  38 kDa

• Isotype:

  IgG