Control Normal llama IgG3

• Background:

  Comparative studies of old world camelids (Camelus bactrianus and Camelus dromedarius) and new world camelids (Lama pacos, Lama glama and Lama vicugna) have shown that heavy-chain-only immunoglobulins represent between 35% - 70% of total IgG in the sera of all species. Such antibodies are homodimers of heavy chains that lack the CH1 domain of conventional antibodies and therefore do not interact with light chains, exhibiting a lower molecular weight ~100 kDa. In llama and other species of camelids, these heavy-chain-only immunoglobulins belong to the IgG2 and IgG3 subclasses of gamma chain antibodies.

• Host:

  Llama

• Type:

  Control Antibodies

• Concentration:

  1 mg/mL

• Buffer:

  0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store vial at -20˚ C prior to opening. Aliquot contents and freeze at -20˚ C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4˚ C as an undiluted liquid. Dilute only prior to immediate use.

• Calculated Molecular Weight:

  319.9 . 196.0

• Fragment:

  IgG3

• Applications Notes:

  Llama IgG3 isotype control can be utilized as a control or standard reagent in Flow Cytometry, Western Blotting, and ELISA experiments where determination of sample isotype is important.

• Tested Applications:

  ELISA, WB, Flow

• Physical Properties:

  Liquid