SARS-CoV-2 (COVID-19) Spike G142D Δ143-145VYY Peptide (Omicron)

• Background:

  SARS-CoV-2 Omicron variant, a variant of concern (VOC), known as B.1.1.529, was detected in South Africa at the end of November in 2021. However, it rapidly spread all over of the world and now it is the dominant variant in the world, which account for more than 90% of the new cases. Omicron variant spike protein carries around 30 amino acid changes, including mutations, deletions and insertions, 15 of which are in the receptor binding domain (RBD) . Enhanced transmission of the Omicron variant was observed globally, which is at least 70 times more contagious than the other variants. The Omicron variant affects the effectiveness of COVID-19 vaccine and is resistant to neutralization (monoclonal antibody treatments) to a large extent.

• NCBI Gene ID:

  43740568

• Swiss Prot:

  P0DTC2

• Accession Number:

  QHD43416

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store SARS-CoV-2 (COVID-19) Spike G142D Δ143-145VYY Peptide (Omicron) at -20˚ C, stable for one year.

• Applications Notes:

  SARS-CoV-2 (COVID-19) Spike G142D Δ143-145VYY Peptide (Omicron) is used for blocking the activity of theSARS-CoV-2 (COVID-19) Spike G142D Δ143-145VYY Antibody (Omicron)

• NCBI Official Name:

  Surface glycoprotein

• NCBI Organism:

  Severe acute respiratory syndrome coronavirus 2

• Background Reference 01:

  Gowrisankar et al. European Physical Journal Plus, 2022, 137 (1), 100.

• Background Reference 02:

  Zhang et al. PNAS of U.S.A. 2021, 118 (47) :e2109905118.

• Background Reference 03:

  Cameroni et al. Nature 2021.

• Background Reference 04:

  Rossler et al. NEJM 2022.

• Background Reference 05:

  Muik et al. Science 2022.

• Other Product Names:

  SARS-CoV-2 Omicron Variant Spike antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein, Omicron Variant

• Tested Applications:

  Blocking

• Species:

  SARS-CoV-2

• Protein ID:

  1791269090

• Physical Properties:

  Liquid