SARS-CoV-2 (COVID-19) NSP15 Peptide

• Background:

  Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP15 is a Mn2+-dependent, uridylate-specific enzyme, which leaves 2'-3'-cyclic phosphates 5' to the cleaved bond.

• NCBI Gene ID:

  43740578

• Swiss Prot:

  P0DTC1

• Accession Number:

  6VWW_B

• Type:

  Peptides

• Concentration:

  200 ug/mL

• Buffer:

  PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store SARS-CoV-2 (COVID-19) NSP15 Peptide at -20˚ C, stable for one year.

• Applications Notes:

  SARS-CoV-2 (COVID-19) NSP15 Peptideis used for blocking the activity of theSARS-CoV-2 (COVID-19) NSP15 Antibody

• NCBI Official Name:

  ORF1a polyprotein; ORF1ab polyprotein

• NCBI Organism:

  Severe acute respiratory syndrome coronavirus 2

• Background Reference 01:

  Gorbalenya. bioRxiv: 2020.

• Background Reference 02:

  Hui et al. Int J Infect Dis. 2020;91:264-266.

• Other Product Names:

  Uridylate-specific endoribonuclease, NendoU, NSP15, Non-structure protein 15

• Tested Applications:

  Blocking

• Species:

  SARS-CoV-3

• Protein ID:

  1851775710

• Physical Properties:

  Liquid