IGF-BP1 Recombinant Protein

• Background:

  IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, where as nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a 25.4 kDa protein consisting of 235 amino acid residues (Isoform A) .

• NCBI Gene ID:

  3484

• Swiss Prot:

  P08833

• Accession Number:

  NP_000587.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Cancer, Growth Factors, Immunology, Signal Transduction

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized IGF-BP1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted IGF-BP1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing IGF-BP1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Insulin-like growth factor binding protein 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AFBP, IBP1, PP12, IGF-BP25, hIGFBP-1, Insulin-like growth factor-binding protein 1, Placental protein 12, IBP-1

• Species:

  Human

• Protein ID:

  4504615

• Physical Properties:

  Lyophilized