Trefoil Factor 3 Recombinant Protein

• Background:

  The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF-3 is expressed by goblet cells and in the uterus, and has also been shown to express in certain cancers, including colorectal, hepatocellular, and in biliary tumors. TFF3 may be useful as a molecular marker for certain types of cancer, but its role, if any, in tumorigenesis is unknown. TFF3 also promotes airway epithelial cell migration and differentiation. Recombinant human TFF3 is a 13.2 kDa homodimeric protein consisting of two 59 amino acid chains, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

• NCBI Gene ID:

  7033

• Swiss Prot:

  Q07654

• Accession Number:

  NP_003217.3

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Homeostasis

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized Trefoil Factor 3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Trefoil Factor 3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Trefoil Factor 3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Trefoil factor 3 (intestinal)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ITF, P1B, TFI, ITF, Trefoil factor 3, Intestinal trefoil factor, hITF

• Species:

  Human

• Protein ID:

  281485608

• Physical Properties:

  Lyophilized