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SDLL-4 Recombinant Protein

CAT: 0223-40-235-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-235-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human sDLL4 comprises the extracellular signaling domain of DLL, a member of a structurally-related family of single-pass type I trans-membrane proteins that serve as ligands for Notch receptors. DLL4 functions to specifically activate the Notch-1 and Notch-4 receptors. The Notch signaling pathway regulates endothelial-cell differentiation, proliferation and apoptosis, and is essential for the development, maintenance and remodeling of the vascular system. Targeted deletion of the DLL4 gene in mice resulted in severe vascular defects and death before birth. Up-regulation of DLL4 expression has been implicated in the vascular development of certain tumors. Recombinant human sDLL4 is a 54.0 kDa glycoprotein containing 498 amino-acid residues.
NCBI Gene ID
54567
Swiss Prot
Q9NR61
Accession Number
NP_061947.1
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Chemokines & Cytokines, Immunology, Stem Cell
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized sDLL-4 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted sDLL-4 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing sDLL-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Delta-like 4 (Drosophila)
NCBI Organism
Homo sapiens
Other Product Names
Hdelta2, Delta-like protein 4, Drosophila Delta homolog 4, Delta4
Species
Human
Protein ID
9506545
Physical Properties
Lyophilized

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