Influenza A virus Neuraminidase Recombinant Protein

• Background:

  Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

• Swiss Prot:

  H8PF47

• Accession Number:

  H8PF47_9INFA, GISAID

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Infectious Disease

• Purity:

  >90% as determined by SDS-PAGE.

• Buffer:

  Supplied as 0.2 μm filtered solution in PBS, pH7.4, 300 mM NaCl with trehalose as protectant.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Protein MUST be stored at -70˚ C or lower upon receipt. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  The protein has a calculated MW of 53.2 kDa. The protein migrates as 65 kDa when calibrated against pre-stained protein marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• Background Reference 01:

  Manz B., et al., 2012, Submitted to the EMBL/GenBank/DDBJ databases.

• Other Product Names:

  NA, Neuraminidase

• Tested Applications:

  WB

• Species:

  Influenza A

• Physical Properties:

  Liquid