IL-2 Antibody

• Background:

  Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7) . The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.

• NCBI Gene ID:

  16183

• Swiss Prot:

  P04351

• Accession Number:

  P04351

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIL-2 (murine Interleukin-2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Functional Antibodies, Antibody Pairs

• Field of Research:

  Immunology, Chemokines & Cytokines

• Purification:

  Anti-mIL-2 specific antibody was purified by affinity chromatography employing immobilized mIL-2 matrix.

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  IL-2 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  Il2

• NCBI Official Name:

  Interleukin 2

• NCBI Organism:

  Mus musculus

• Other Product Names:

  Il-2, Il-2, Interleukin-2, T-cell growth factor, IL-2

• Tested Applications:

  ELISA, WB, Neutralization Assay

• Protein ID:

  124326

• Physical Properties:

  Lyophilized