IL-11 Antibody

• Background:

  Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.

• NCBI Gene ID:

  3589

• Swiss Prot:

  P20809

• Accession Number:

  P20809

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIL-11 (human Interleukin-11) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Functional Antibodies, Antibody Pairs

• Field of Research:

  Immunology, Chemokines & Cytokines, Neuroscience

• Purification:

  Anti-hIL-11 specific antibody was purified by affinity chromatography employing immobilized hIL-11 matrix.

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  IL-11 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  IL11

• NCBI Official Name:

  Interleukin 11

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  AGIF, IL-11Interleukin-11, Adipogenesis inhibitory factor, IL-11

• Tested Applications:

  ELISA, WB, Neutralization Assay

• Protein ID:

  124294

• Physical Properties:

  Lyophilized