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CD4 Antibody [9H5A8]

CAT: 0223-PM-5201-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-PM-5201-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD4 Monoclonal Antibody: CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.
NCBI Gene ID
920
Swiss Prot
P01730
Accession Number
NP_000607
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Mouse monoclonal CD4 antibody was raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.
Clonality
Monoclonal
Clone
9H5A8
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Recombinant Protein Test (Figure 1) : Anti-CD4 antibodies (PM-5201) detected human CD-4 recombinant protein at 5ng. Recombinant Protein TestPM-5201
Field of Research
Immunology
Purification
CD4 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
Positive Control
Cat. No. 1314 - Human Thymus Tissue Lysate
Concentration
1 mg/mL
Buffer
CD4 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CD4 monoclonal antibody can be stored at -20˚ C, stable for one year.
Fragment
IgG1
Isoform
Human CD4 has one isoform (458aa, 51kD) . Mouse CD4 has two isoforms, including isoform 1 (457aa, 51kD) and isoform 2 (217aa, 24.5kD) . Rat CD4 has one isoform (457aa, 51kD) . PM-5201 can detect human, mouse and rat.
Symbol
CD4
Positive Control 2
Cat. No. 1205 - Jurkat Cell Lysate
NCBI Official Name
CD4 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Bowers et al. Int. J. Biochem. Cell Biol. 1997; 29 :871-5.
Background Reference 02
Arthos et al. Cell 1989; 57:469-81.
Citation 01
22954649
Other Product Names
CD4 Antibody [9H5A8] : CD4mut
Tested Applications
ELISA, WB, IHC-P
Protein ID
10835167
Physical Properties
Liquid

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