CD86 Antibody [2D10]

• Background:

  CD86 (B7-2) is an 80 kDa type I integral membrane protein and a member of the immunoglobulin superfamily of cell surface receptors. Along with CD80 (B7-1), CD86 participates in T cell costimulation via interaction with CD28 and CD152 (CTLA-4) . It is expressed at very low density in normal tissues but is rapidly upregulated on stimulated B cells, monocytes, and dendritic cells. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response.

• NCBI Gene ID:

  12524

• Swiss Prot:

  P42082

• Accession Number:

  P42082

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  Mouse B cell lymphoma cell line 5C2

• Clonality:

  Monoclonal

• Clone:

  [2D10]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Innate Immunity

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2b

• Specificity:

  CD86

• Applications Notes:

  CD86 Antibody [2D10] for use in flow cytometry, immunohistochemistry, immunoprecipitation, ELISA, separation, CMCD, and blocking assays.

• Symbol:

  Cd86

• NCBI Official Name:

  CD86 antigen

• NCBI Organism:

  Mus musculus

• Other Product Names:

  B7-2, B70, Ly-58

• Tested Applications:

  Flow

• Physical Properties:

  Liquid