NKG2-A/C/E Antibody [20d5] (Biotin)

• Background:

  The monoclonal antibody 20d5 reacts with an epitope common to the NKG2A, NKG2C and NKG2E isoforms of the NKG2 heterodimer, a member of the c-type lectin family of inhibitory receptors. Mouse NKG2 is a natural killer (NK) cell receptor for the non-classical MHC class I molecule Qa-1b. NKG2 is expressed on NK cells, lymphokine-activated killer (LAK) T cells, and some CD8+ memory T cells. Two-color immunofluorescent staining with the 20d5 antibody reveals two distinct NKG2+ phenotypes within the NK1.1+CD3- spleen cell population: NKG2hi (50%) and NKG2low (50%) . With the exception of DBA/2J mice, NKG2 is expressed on NK1.1+ cells from all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL) .

• NCBI Gene ID:

  16641;16642;58179

• Host:

  Rat

• Reactivity:

  Mouse

• Immunogen:

  CHO cells transfected with B6 allele of NKG2A gene

• Clonality:

  Monoclonal

• Clone:

  [20d5]

• Conjugation:

  Biotin

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in PBS/NaN3

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2a

• Specificity:

  NKG2-A/C/E

• Applications Notes:

  NKG2-A/C/E Antibody [20d5] for use in flow cytometry assays.

• Symbol:

  Klrc1

• NCBI Official Name:

  Killer cell lectin-like receptor subfamily C, member 1

• NCBI Organism:

  Mus musculus

• Other Product Names:

  NKG2A, NKG2C, NKG2E

• Tested Applications:

  IHC-P, IHC-Fr, Flow, Blocking, IP, Cytotoxicity Assay, Separation

• Physical Properties:

  Liquid