CD45R Antibody [RA3-6B2] (APC-Cy5.5)

• Background:

  CD45R, also known as B220, a member of the protein tyrosine phosphate family and a major cell surface glycoprotein, represents a restricted form of the CD45 family which primarily recognizes only cells of B-lineage from pro-B cell through mature B lymphocytes and prior to the availability of anti-CD19 monoclonal antibodies was commonly used as a pan B-cell marker. It also reacts with certain activated T cells as well as non-MHC-restricted lytically active lymphokine-activated killer (LAK) cells. In vivo administration of RA3-6B2 has been shown to affect differentiation of both T and B cells in normal mice and reduce the level of anti-DNA antibodies and lymphadenopathies in MRL/lpr mice.

• NCBI Gene ID:

  19264

• Swiss Prot:

  P06800

• Accession Number:

  P06800

• Host:

  Rat

• Reactivity:

  Mouse, Human, Cat

• Immunogen:

  Abelson murine leukemia virus-induced pre-B cell lymphoma

• Clonality:

  Monoclonal

• Clone:

  [RA3-6B2]

• Conjugation:

  APC-Cy5.5

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Concentration:

  0.1 mg/mL

• Buffer:

  Supplied in PBS/NaN3 and a stabilizing agent

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2a

• Specificity:

  CD45R

• Applications Notes:

  CD45R Antibody [RA3-6B2] for use in flow cytometry assays.

• Symbol:

  Ptprc

• NCBI Official Name:

  Protein tyrosine phosphatase, receptor type, C

• NCBI Organism:

  Mus musculus

• Other Product Names:

  B220, Ly-5, Lyt-4, Ptprc, Receptor-type tyrosine-protein phosphatase C

• Tested Applications:

  Flow

• Physical Properties:

  Liquid