CD11a Antibody [I21/7]

• Background:

  The monoclonal antibody I21/7 reacts with the alpha subunit of mouse and human CD11a, also known as LFA-1, and a member of the integrin family of cell adhesion molecules. The antigen is expressed on thymocytes, T and B lymphocytes, and on non-lymphoid cells in the bone marrow. CD11a appears to be an essential component for T-cell activation by antigen-presenting cells and is important for cell-mediated killing. Costimulatory signaling by LFA-1 is achieved by pairing with its ligand, CD54/ICAM-1.

• NCBI Gene ID:

  16408

• Swiss Prot:

  P24063

• Accession Number:

  P24063

• Host:

  Rat

• Reactivity:

  Mouse, Human

• Immunogen:

  Whole BW5147 cells

• Clonality:

  Monoclonal

• Clone:

  [I21/7]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Concentration:

  0.5 mg/mL

• Buffer:

  Supplied in PBS

• Modification:

  None

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Store vial at -20˚ C

• Fragment:

  IgG2a

• Specificity:

  CD11a

• Applications Notes:

  CD11a Antibody [I21/7] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, and blocking assays.

• Symbol:

  Itgal

• NCBI Official Name:

  Integrin alpha L

• NCBI Organism:

  Mus musculus

• Other Product Names:

  LFA-1, LFA-1alpha, integrin alphaL

• Tested Applications:

  ELISA

• Physical Properties:

  Liquid