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CD3e Antibody [C363.29B] (APC)

CAT: 0223-98-579Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-98-579Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR) . It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naïve T cell in vitro. Immobilized C363.2B9 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. The monoclonal antibody is cytolytic, easily used for cell surface staining, and a good immunoprecipitating antibody.
NCBI Gene ID
12501
Swiss Prot
P22646
Accession Number
P22646
Host
Rat
Reactivity
Mouse
Immunogen
IL-4 producing Th2 cell lines including D10
Clonality
Monoclonal
Clone
[C363.29B]
Conjugation
APC
Type
Primary Antibodies
Field of Research
Immunology
Concentration
0.1 mg/mL
Buffer
Supplied in PBS/NaN3 and a stabilizing agent
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store vial at 2-8˚ C
Fragment
IgG2b
Specificity
CD3epsilon
Applications Notes
CD3e Antibody [C363.29B] for use in flow cytometry assays.
Symbol
Cd3e
NCBI Official Name
CD3 antigen, epsilon polypeptide
NCBI Organism
Mus musculus
Other Product Names
CD3 epsilon
Tested Applications
Flow
Physical Properties
Liquid

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