MELK Antibody

• Background:

  Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis.

• NCBI Gene ID:

  9833

• Swiss Prot:

  Q14680

• Accession Number:

  NP_055606.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  MELK antibody was raised against a peptide sequence around aa.626~630 (I-R-R-Q-R) derived from Human MELK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Stem Cell

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  74 kDa

• Specificity:

  This antibody detects endogenous level of total MELK protein.

• Applications Notes:

  Western Blot: 1:500

• Symbol:

  MELK

• NCBI Official Name:

  Maternal embryonic leucine zipper kinase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Seong H. -A., Gil M., Kim K. -T., Kim S. -J., Ha H. Biochem. J. 361:597-604 (2002) Vulsteke V., Beullens M., Boudrez A., Keppens S., Van Eynde A., Rider M. H., Stalmans W., Bollen M. J. Biol. Chem. 279:8642-8647 (2004)

• Other Product Names:

  HPK38, hPK38, KIAA0175, hMELK

• Tested Applications:

  WB

• Protein ID:

  7661974

• Physical Properties:

  Liquid