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ABCG2 (CD338) Antibody

CAT: 0223-79-673Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-673Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.
NCBI Gene ID
9429
Swiss Prot
Q9UNQ0
Accession Number
NP_004818.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
ABCG2 (CD338) antibody was raised against a peptide sequence around aa.160~164 (R-I-N-R-V) derived from Human ABCG2 (CD338) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
65 - 80 kDa
Specificity
This antibody detects endogenous level of total ABCG2 (CD338) protein.
Applications Notes
Western Blot: 1:500
Symbol
ABCG2
NCBI Official Name
ATP-binding cassette, sub-family G (WHITE), member 2
NCBI Organism
Homo sapiens
Background Reference 01
Henriksen U., Gether U., Litman T. J. Cell Sci. 118:1417-1426 (2005) Wakabayashi K., Nakagawa H., Tamura A., Koshiba S., Hoshijima K., Komada M., Ishikawa T. J. Biol. Chem. 282:27841-27846 (2007)
Other Product Names
MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, GOUT1, CDw338, UAQTL1, EST157481, MRX
Tested Applications
WB
Protein ID
62526033
Physical Properties
Liquid

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