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MCL1 Antibody

CAT: 0223-79-656Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-79-656Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
NCBI Gene ID
4170
Swiss Prot
Q07820
Accession Number
NP_068779.1
Host
Rabbit
Reactivity
Human
Immunogen
MCL1 antibody was raised against a peptide sequence around aa.148~152 (N-N-T-S-T) derived from Human MCL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
42 kDa
Specificity
This antibody detects endogenous level of total MCL1 protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
MCL1
NCBI Official Name
Myeloid cell leukemia sequence 1 (BCL2-related)
NCBI Organism
Homo sapiens
Background Reference 01
Bingle C. D., Craig R. W., Swales B. M., Singleton V., Zhou P., Whyle M. K. B. J. Biol. Chem. 275:22136-22146 (2000)
Other Product Names
TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, TUBB4, TM
Tested Applications
WB
Protein ID
11386165
Physical Properties
Liquid

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