MCL1 Antibody

• Background:

  Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

• NCBI Gene ID:

  4170

• Swiss Prot:

  Q07820

• Accession Number:

  NP_068779.1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  MCL1 antibody was raised against a peptide sequence around aa.148~152 (N-N-T-S-T) derived from Human MCL1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  42 kDa

• Specificity:

  This antibody detects endogenous level of total MCL1 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  MCL1

• NCBI Official Name:

  Myeloid cell leukemia sequence 1 (BCL2-related)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Bingle C. D., Craig R. W., Swales B. M., Singleton V., Zhou P., Whyle M. K. B. J. Biol. Chem. 275:22136-22146 (2000)

• Other Product Names:

  TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT, TUBB4, TM

• Tested Applications:

  WB

• Protein ID:

  11386165

• Physical Properties:

  Liquid