SOX2 Antibody

• Background:

  Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency

• NCBI Gene ID:

  6657

• Swiss Prot:

  P48431

• Accession Number:

  NP_003097.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  SOX2 antibody was raised against a peptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Stem Cell

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  35 kDa

• Specificity:

  This antibody detects endogenous level of total SOX2 protein.

• Applications Notes:

  Western Blot: 1:1000

• Symbol:

  SOX2

• NCBI Official Name:

  SRY (sex determining region Y) -box 2

• NCBI Organism:

  This antibody was raised against a peptide sequence around aa.76~80 (G-A-E-W-K) derived from SOX2

• Background Reference 01:

  Yuan H, et al. Genes Dev. 1995 Nov 1;9 (21) : 2635-45Muta M, et al. Genes Cells 2002 Aug;7 (8) : 791-805 Tomioka M, et al. Nucleic Acids Res. 2002 Jul 15; 30 (14) : 3202-3213.

• Other Product Names:

  ANOP3, MCOPS3, HER2, MLN19, NEU, NGL, Transcription factor SOX-2

• Tested Applications:

  WB

• Protein ID:

  28195386

• Physical Properties:

  Liquid