Ephrin B2 (Ab 316) Antibody

• Background:

  Ephrin-B2 encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a lycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.

• NCBI Gene ID:

  1948

• Swiss Prot:

  P52799

• Accession Number:

  NP_004084.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Ephrin-B2 (Ab-316) antibody was raised against a peptide sequence around aa.314~318 (P-V-Y-I-V) derived from Human Ephrin B (ephrin-B2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  37 kDa

• Specificity:

  This antibody detects endogenous level of total Ephrin-B2 protein.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  EFNB2

• NCBI Official Name:

  Ephrin-B2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chrencik JE, et al. (2006) J Biol Chem;281 (38) : 28185-28192. Kertesz N, et al. (2006) Blood;107 (6) : 2330-2338. Noren NK, et al. (2004) Proc Natl Acad Sci USA;101 (15) : 5583-5588.

• Other Product Names:

  HTKL, EPLG5, Htk-L, LERK5, EFNB2, HTKL, LERK5

• Tested Applications:

  WB

• Protein ID:

  4758250

• Physical Properties:

  Liquid