Smad1 (phospho Ser465) Antibody

• Background:

  Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) .

• NCBI Gene ID:

  4086

• Swiss Prot:

  Q15797

• Accession Number:

  NP_001003688.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Smad1 (Phospho-Ser465) antibody was raised against a peptide sequence around phosphorylation site of serine 465 (I-S-S-V-S (p) ) derived from Human Smad1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Phospho-Specific

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  Phospho-Specific

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  55 kDa

• Specificity:

  This antibody detects endogenous level of Smad1 only when phosphorylated at serine 465.

• Applications Notes:

  Western Blot: 1:500~1:1000

• Symbol:

  SMAD1

• NCBI Official Name:

  SMAD family member 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hiroaki Seto, et al. (2004) J Clin Invest. March 1; 113 (5) : 718–726Linyu Li, et al. (2004) Mol Cell Biol. January; 24 (2) : 856–864. Claire Nourry, et al. (2004) BMC Cell Biol. 5: 20

• Other Product Names:

  BSP1, JV41, BSP-1, JV4-1, MADH1, MADR1, ERBB, ERBB1, HER1, BSP1, Dwarfin-A, Dwf-A

• Tested Applications:

  WB

• Protein ID:

  51173727

• Physical Properties:

  Liquid