CD69 Antibody [FN50] (PE)

• Background:

  The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) . It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.

• NCBI Gene ID:

  969

• Swiss Prot:

  Q07108

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  FN50

• Conjugation:

  PE

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgG1, kappa

• Specificity:

  The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) .

• Symbol:

  CD69

• NCBI Official Name:

  CD69 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Marzio, R., Jirillo, E., Ransijn, A., Mauel, J., Corradin, S. B. (1997) . Expression and function of the early activation antigen CD69 in murine macrophages.Journal of leukocyte biology,62 (3), 349-355.

• Background Reference 02:

  Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M., Stingl, G., Coligan, J. E., Shevach, E. M. (1988) . Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation.The Journal of Immunology,141 (2), 369-376.

• Background Reference 03:

  Sobel, E. S., Yokoyama, W. M., Shevach, E. M., Eisenberg, R. A., Cohen, P. L. (1993) . Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.The Journal of Immunology,150 (2), 673-682.

• Other Product Names:

  AIM, EA1, MLR-3, CLEC2C, GP32/28, BL-AC/P26, CD69

• Tested Applications:

  Flow

• Physical Properties:

  Liquid