CD5 Antibody [UCHT2] (APC)

• Background:

  The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.

• NCBI Gene ID:

  921

• Swiss Prot:

  P06127

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  UCHT2

• Conjugation:

  APC

• Type:

  Primary Antibodies

• Field of Research:

  Immunology

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgG1, kappa

• Specificity:

  The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein.

• Symbol:

  CD5

• NCBI Official Name:

  CD5 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

• Background Reference 02:

  Correia, D. V., Fogli, M., Hudspeth, K., da Silva, M. G., Mavilio, D., Silva-Santos, B. (2011) . Differentiation of human peripheral blood Vdelta-1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells.Blood,118 (4), 992-1001.

• Other Product Names:

  T1, LEU1, CD5

• Tested Applications:

  Flow

• Physical Properties:

  Liquid