CD34 Antibody [4H11] (FITC)

• Background:

  The 4H11 monoclonal antibody specifically reacts with the Class III epitope of CD34 (mucosialin), a transmembrane phosphoglycoprotein. It is expressed on most hematopoietic progenitors, pluripotent stem cells and tumor cells.

• NCBI Gene ID:

  947

• Swiss Prot:

  P28906

• Host:

  Mouse

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Clone:

  4H11

• Conjugation:

  FITC

• Type:

  Primary Antibodies

• Field of Research:

  Innate Immunity, Stem Cell

• Purification:

  The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

• Concentration:

  Batch dependent

• Buffer:

  Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

• Fragment:

  Mouse IgG1, kappa

• Specificity:

  The 4H11 monoclonal antibody specifically reacts with the Class III epitope of CD34 (mucosialin), a transmembrane phosphoglycoprotein.

• Symbol:

  CD34

• NCBI Official Name:

  CD34 molecule

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Elknerov, K., Lacinov, Z., Soucek, J., Marinov, I., Stockbauer, P. (2007) . Growth inhibitory effect of the antibody to hematopoietic stem cell antigen CD34 in leukemic cell lines.NEOPLASMA-BRATISLAVA-,54 (4), 311.

• Background Reference 02:

  Singh, V. K., Tsuji, K., Sharma, P. B., Chandra, R. MULTIDIMENSIONAL ROLE OF CD34 PROTEIN IN HEMATOPOIETIC STEM CELL BIOLOGY.

• Background Reference 03:

  Krause, D. S., Fackler, M. J., Civin, C. I., May, W. S. (1996) . CD34: structure, biology, and clinical utility.Blood,87 (1), 1-13.

• Other Product Names:

  RP11-328D5.2, CD34

• Tested Applications:

  Flow

• Physical Properties:

  Liquid