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CD11c Antibody [3.9]

CAT: 0223-76-141Size: 0.1 mgDry Ice: NoHazardous: No
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CAT#:0223-76-141Size:0.1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X. It is expressed on macrophages, granulocytes, monocytes, dendritic cells, natural killer cells, and subsets of B and T lymphocytes. The CD11c/CD18 complex associates with the iC3b, fibrinogen and ICAM-1 and has an important function in leukocyte adhesion.
NCBI Gene ID
3687
Swiss Prot
P20702
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
3.9
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The 3.9 monoclonal antibody specifically binds to the human adhesion glycoprotein CD11c, a 150 kDA integrin alpha chain also known as integrin alpha X.
Symbol
ITGAX
NCBI Official Name
Integrin, alpha X (complement component 3 receptor 4 subunit)
NCBI Organism
Homo sapiens
Background Reference 01
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 02
Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 03
McMichael, A. J. (1987) . Leucocyte typing III.Oxford University Press, Oxford. Norton AJ, Isaacson PG (1985)
Background Reference 04
Ottonello, L., Epstein, A. L., Dapino, P., Barbera, P., Morone, P., Dallegri, F. (1999) . Monoclonal Lym-1 antibody-dependent cytolysis by neutrophils exposed to granulocyte-macrophage colony-stimulating factor: intervention of Fc-gamma RII (CD32), CD11b-CD18 integrins, and CD66b glycoproteins.Blood,93 (10), 3505-3511.
Other Product Names
CD11C, SLEB6, ITGAX
Tested Applications
Flow, Functional Assays, IF, IP
Physical Properties
Liquid

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