VEGFR2 (Ab 1175) Antibody

• Background:

  Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions

• NCBI Gene ID:

  3791

• Swiss Prot:

  P35968

• Accession Number:

  NP_002244.1

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  VEGFR2 (Ab-1175) antibody was raised against a peptide sequence around aa.1173~1177 (K-D-Y-I-V) derived from Human VEGFR2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  230 kDa

• Specificity:

  This antibody detects endogenous level of total VEGFR2 protein.

• Applications Notes:

  Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

• Symbol:

  KDR

• NCBI Official Name:

  Kinase insert domain receptor (a type III receptor tyrosine kinase)

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lamalice L, et al. (2004) . Oncogene. 23 (2) : 434-445. Takahashi T, et al. (2001) . EMBO J . 20 (11) : 2768-2778.

• Other Product Names:

  FLK1, CD309, VEGFR, VEGFR2, PKD, PKD1, PRKCM, FLK1, KDR, VGFR2, VGR2, kinase insert domain receptor

• Tested Applications:

  IHC, IF

• Protein ID:

  11321597

• Physical Properties:

  Liquid