GNAI3 Antibody

• Background:

  GNα i3, Guanine nucleotide binding protein (G protein), α inhibiting activity polypeptide 3. Gα i3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase following its G-protein coupled receptors (GPCR) such as a2-adrenergic receptors are activated. Gα i3 can be inactivated by pertussis toxin.

• NCBI Gene ID:

  2773

• Swiss Prot:

  P08754

• Accession Number:

  NP_006487.1

• Host:

  Chicken

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  C-terminal peptide (KNNLKECGLY)

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction, Autophagy

• Purification:

  Antigen affinity-purified

• Concentration:

  1 mg/mL

• Buffer:

  Phosphate-Buffered Saline. No preservatives added.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  GNAI3 antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  40.4 kDa (calculated)

• Applications Notes:

  Gai3 antibody can be used for the detection of Gai3 by ICC, may also work for IHC and Wetern blot.

• Symbol:

  GNAI3

• NCBI Official Name:

  Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Miotti, S., Bagnoli, M., Tomassetti, A., Colnaghi, M. I. and Canevari, S. Interaction of folate receptor with signaling molecules lyn and G (alpha) (i-3) in detergent-resistant complexes from the ovary carcinoma cell line IGROV1 J. Cell. Sci. 113 Pt 2, 349-357 (2000) .

• Other Product Names:

  Gai3

• Tested Applications:

  ICC

• Protein ID:

  5729850

• Physical Properties:

  Liquid