DDX6 Antibody

• Background:

  This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing.

• NCBI Gene ID:

  1656

• Swiss Prot:

  P26196

• Accession Number:

  P26196

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 348-375 amino acids from the Central region of human DDX6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  54 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  DDX6

• NCBI Official Name:

  Probable ATP-dependent RNA helicase DDX6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Broytman, O., et al. Neurobiol. Aging 30 (12) :1962-1974 (2009)

• Background Reference 02:

  Han, J.W., et al. Nat. Genet. 41 (11) :1234-1237 (2009)

• Background Reference 03:

  Minshall, N., et al. Mol. Biol. Cell 20 (9) :2464-2472 (2009)

• Background Reference 04:

  Tritschler, F., et al. Mol. Cell 33 (5) :661-668 (2009)

• Other Product Names:

  Probable ATP-dependent RNA helicase DDX6, ATP-dependent RNA helicase p54, DEAD box protein 6, Oncogene RCK, DDX6, HLR2, RCK

• Tested Applications:

  WB, IHC-P

• Protein ID:

  116241327

• Physical Properties:

  Liquid