GNAT1 Antibody

• Background:

  Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells.

• NCBI Gene ID:

  2779

• Swiss Prot:

  P11488

• Accession Number:

  P11488

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GNAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-318 amino acids from the C-terminal region of human GNAT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  40 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GNAT1

• NCBI Official Name:

  Guanine nucleotide-binding protein G (t) subunit alpha-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Luttrell, L.M. Mol. Biotechnol. 39 (3) :239-264 (2008)

• Background Reference 02:

  Szabo, V., et al. Hum. Mutat. 28 (7) :741-742 (2007)

• Background Reference 03:

  Yi, H.M., et al. Ai Zheng 26 (1) :9-14 (2007)

• Background Reference 04:

  Oldham, W.M., et al. Nat. Struct. Mol. Biol. 13 (9) :772-777 (2006)

• Other Product Names:

  Guanine nucleotide-binding protein G (t) subunit alpha-1, Transducin alpha-1 chain, GNAT1, GNATR

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  121032

• Physical Properties:

  Liquid