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AGR3 Antibody

CAT: 0223-63-940Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-940Size:400 µL
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Background
AGR3 (Anterior Gradient 3) protein, also known as AG3 (hAG3, HAG3 in human), or BCMP11, is a secreted cytoplasmic protein which is involved in metastasis induction and p53 tumour supressor inhibition. It may serve as molecular marker and potential therapeutic target for hormone-responsive breast tumours. Its Xenopus homolog is associated with anteroposterior fate determination during early development.
NCBI Gene ID
155465
Swiss Prot
Q8TD06
Accession Number
Q8TD06
Host
Rabbit
Reactivity
Human
Immunogen
This AGR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the C-terminal region of human AGR3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
19 kDa
Fragment
Rabbit Ig
Symbol
AGR3
NCBI Official Name
Anterior gradient protein 3 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Persson, S., et al. Mol. Phylogenet. Evol. 36 (3) :734-740 (2005)
Background Reference 02
Zhang, Z., et al. Protein Sci. 13 (10) :2819-2824 (2004)
Background Reference 03
Clark, H.F., et al. Genome Res. 13 (10) :2265-2270 (2003)
Background Reference 04
Fletcher, G.C., et al. Br. J. Cancer 88 (4) :579-585 (2003)
Other Product Names
Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11
Tested Applications
WB, IHC-P, Flow
Protein ID
66774045
Physical Properties
Liquid

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