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GPX1 Antibody

CAT: 0223-63-890Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-890Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GPX1 encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence.
NCBI Gene ID
2876
Swiss Prot
P07203
Accession Number
P07203
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This GPX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human GPX1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
GPX1
NCBI Official Name
Glutathione peroxidase 1
NCBI Organism
Homo sapiens
Background Reference 01
Moyer, A.M., et.al., Cancer Epidemiol. Biomarkers Prev. 19 (3), 811-821 (2010)
Background Reference 02
Akimoto, A.K., et.al., Free Radic. Res. 44 (3), 322-331 (2010)
Background Reference 03
Cao, C., et.al., J. Biol. Chem. 278 (41), 39609-39614 (2003)
Other Product Names
Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase, GPX1
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
311033481
Physical Properties
Liquid

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