GPX1 Antibody

• Background:

  GPX1 encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence.

• NCBI Gene ID:

  2876

• Swiss Prot:

  P07203

• Accession Number:

  P07203

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  This GPX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-193 amino acids from the C-terminal region of human GPX1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  22 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GPX1

• NCBI Official Name:

  Glutathione peroxidase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Moyer, A.M., et.al., Cancer Epidemiol. Biomarkers Prev. 19 (3), 811-821 (2010)

• Background Reference 02:

  Akimoto, A.K., et.al., Free Radic. Res. 44 (3), 322-331 (2010)

• Background Reference 03:

  Cao, C., et.al., J. Biol. Chem. 278 (41), 39609-39614 (2003)

• Other Product Names:

  Glutathione peroxidase 1, GPx-1, GSHPx-1, Cellular glutathione peroxidase, GPX1

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  311033481

• Physical Properties:

  Liquid