MARK2 Antibody

• Background :

  Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

• NCBI Gene ID :

  2011

• Swiss Prot :

  Q7KZI7

• Accession Number :

  Q7KZI7

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This MARK2 (EMK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 600-630 amino acids from the C-terminal region of human MARK2 (EMK) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  88 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  MARK2

• NCBI Official Name :

  Serine/threonine-protein kinase MARK2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Blume-Jensen P, et al. Nature 2001. 411: 355.

• Background Reference 02 :

  Cantrell D, J. Cell Sci. 2001. 114: 1439.

• Background Reference 03 :

  JhiangOncogene 2000. 19: 5590.

• Background Reference 04 :

  Manning G, et al. Science 2002. 298: 1912.

• Other Product Names :

  Serine/threonine-protein kinase MARK2, ELKL motif kinase 1, EMK-1, MAP/microtubule affinity-regulating kinase 2, PAR1 homolog, PAR1 homolog b, Par-1b, Par1b, MARK2 {ECO:0000312|EMBL:AAH087712}, EMK1

• Tested Applications :

  WB, IHC-P

• Protein ID :

  62510922

• Physical Properties :

  Liquid