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IGFBP3 Antibody

CAT: 0223-63-090Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-090Size:400 µL
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Background
IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
NCBI Gene ID
3486
Swiss Prot
P17936
Accession Number
P17936
Host
Rabbit
Reactivity
Human
Immunogen
This IGFBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-193 amino acids from the N-terminal region of human IGFBP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
32 kDa
Fragment
Rabbit Ig
Symbol
IGFBP3
NCBI Official Name
Insulin-like growth factor-binding protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Muzumdar, R.H., Diabetes 55 (10), 2788-2796 (2006)
Background Reference 02
Novosyadlyy, R., Growth Horm. IGF Res. 15 (5), 313-323 (2005)
Other Product Names
Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3, IGFBP3, IBP3
Tested Applications
WB, IHC-P
Protein ID
146327827
Physical Properties
Liquid

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