CLIC1 Antibody

• Background:

  Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.

• NCBI Gene ID:

  1192

• Swiss Prot:

  O00299

• Accession Number:

  O00299

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CLIC1 antibody is generated from rabbits immunized with a recombinant human CLIC1 protein.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  27 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CLIC1

• NCBI Official Name:

  Chloride intracellular channel protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Singh, H., FEBS J. 274 (24), 6306-6316 (2007)

• Background Reference 02:

  Ulmasov, B., (er) BMC Cell Biol. 8, (2007)

• Background Reference 03:

  Edwards, J.C., J. Membr. Biol. 213 (1), 39-46 (2006)

• Other Product Names:

  Chloride intracellular channel protein 1, Chloride channel ABP, Nuclear chloride ion channel 27, NCC27, Regulatory nuclear chloride ion channel protein, hRNCC, CLIC1, G6, NCC27

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid