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ACAT1 Antibody

CAT: 0223-62-991Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-991Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in the gene encoding ACAT1 are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.
NCBI Gene ID
38
Swiss Prot
P24752
Accession Number
P24752
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ACAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-329 amino acids from the C-terminal region of human ACAT1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Symbol
ACAT1
NCBI Official Name
Acetyl-CoA acetyltransferase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Locke, J.A., Prostate 68 (1), 20-33 (2008)
Background Reference 02
Guo, Z.Y., Biochemistry 46 (35), 10063-10071 (2007)
Background Reference 03
Haapalainen, A.M., Biochemistry 46 (14), 4305-4321 (2007)
Other Product Names
Acetyl-CoA acetyltransferase, mitochondrial, Acetoacetyl-CoA thiolase, T2, ACAT1, ACAT, MAT
Tested Applications
WB, IHC-P
Protein ID
135755
Physical Properties
Liquid

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