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PLG Antibody

CAT: 0223-62-815Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-815Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PLG is a circulating zymogen that is converted to the active enzyme plasmin by cleavage of the peptide bond between arg560 and val561, which is mediated by urokinase and tissue plasminogen activator. The main function of this protein is to dissolve fibrin clots. The protein, like trypsin, belongs to the family of serine proteinases.
NCBI Gene ID
5340
Swiss Prot
P00747
Accession Number
P00747
Host
Rabbit
Reactivity
Human
Immunogen
This PLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 636-665 amino acids from the C-terminal region of human PLG.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
91 kDa
Fragment
Rabbit Ig
Symbol
PLG
NCBI Official Name
Plasminogen
NCBI Organism
Homo sapiens
Background Reference 01
Hofmann, S.C., Voith, U. J. Invest. Dermatol. 129 (7), 1730-1739 (2009)
Background Reference 02
Passero, C.J., Mueller, G.M. J. Biol. Chem. 283 (52), 36586-36591 (2008)
Background Reference 03
Ohyama, S., Harada, T. Eur. J. Biochem. 271 (4), 809-820 (2004)
Background Reference 04
Lee, H., Kim, H.K. Arch. Biochem. Biophys. 375 (2), 359-363 (2000)
Other Product Names
Plasminogen, Plasmin heavy chain A, Activation peptide, Angiostatin, Plasmin heavy chain A, short form, Plasmin light chain B, PLG
Tested Applications
WB, IHC-P, Flow
Protein ID
130316
Physical Properties
Liquid

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