ADRB2 Antibody

• Background:

  ADRB2, beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca (V) 1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This protein is intronless.

• NCBI Gene ID:

  154

• Swiss Prot:

  P07550

• Accession Number:

  P07550

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ADRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-373 amino acids from human ADRB2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  46 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ADRB2

• NCBI Official Name:

  Beta-2 adrenergic receptor

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kobilka B.K., Dixon R.A.F.Proc. Natl. Acad. Sci. U.S.A. 84:46-50 (1987)

• Background Reference 02:

  Emorine L.J., Marullo S.Proc. Natl. Acad. Sci. U.S.A. 84:6995-6999 (1987)

• Background Reference 03:

  Kobilka B.K., Frielle T.J. Biol. Chem. 262:7321-7327 (1987)

• Other Product Names:

  Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2, ADRB2R, B2AR

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  296439450

• Physical Properties:

  Liquid