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MELK Antibody

CAT: 223-62-687Size: 400 µLDry Ice: NoHazardous: No
400 µLSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MELK contains 1 protein kinase domain that belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis.
NCBI Gene ID
9833
Swiss Prot
Q14680
Accession Number
Q14680
Host
Rabbit
Reactivity
Human
Immunogen
This MELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human MELK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
75 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MELK
NCBI Official Name
Maternal embryonic leucine zipper kinase
NCBI Organism
Homo sapiens
Background Reference 01
Davezac, N., et al., Oncogene 21 (50) :7630-7641 (2002) .
Background Reference 02
Heyer, B.S., et al., Mol. Reprod. Dev. 47 (2) :148-156 (1997) .
Other Product Names
Maternal embryonic leucine zipper kinase, hMELK, Protein kinase Eg3, pEg3 kinase, Protein kinase PK38, hPK38, Tyrosine-protein kinase MELK, MELK, KIAA0175
Tested Applications
WB
Protein ID
50400857
Physical Properties
Liquid

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