MELK Antibody

• Background:

  MELK contains 1 protein kinase domain that belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis.

• NCBI Gene ID:

  9833

• Swiss Prot:

  Q14680

• Accession Number:

  Q14680

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MELK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human MELK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Cell Cycle, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  75 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MELK

• NCBI Official Name:

  Maternal embryonic leucine zipper kinase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Davezac, N., et al., Oncogene 21 (50) :7630-7641 (2002) .

• Background Reference 02:

  Heyer, B.S., et al., Mol. Reprod. Dev. 47 (2) :148-156 (1997) .

• Other Product Names:

  Maternal embryonic leucine zipper kinase, hMELK, Protein kinase Eg3, pEg3 kinase, Protein kinase PK38, hPK38, Tyrosine-protein kinase MELK, MELK, KIAA0175

• Tested Applications:

  WB

• Protein ID:

  50400857

• Physical Properties:

  Liquid