Guanylyl Cyclase alpha 1 Antibody

• Background:

  Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

• NCBI Gene ID:

  2982

• Swiss Prot:

  Q02108

• Accession Number:

  Q02108

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This Guanylyl Cyclase alpha 1 (GUCY1A3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-300 amino acids from the N-terminal region of human Guanylyl Cyclase alpha 1 (GUCY1A3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  77 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  GUCY1A3

• NCBI Official Name:

  Guanylate cyclase soluble subunit alpha-3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Saino, M., et al., Oncol. Rep. 12 (1) :47-52 (2004) .

• Background Reference 02:

  Zhou, Y., et al., Gene 245 (2) :319-328 (2000) .

• Background Reference 03:

  Papapetropoulos, A., et al., J. Cell. Physiol. 167 (2) :213-221 (1996) .

• Background Reference 04:

  Giuili, G., et al., Hum. Genet. 91 (3) :257-260 (1993) .

• Other Product Names:

  Guanylate cyclase soluble subunit alpha-3, GCS-alpha-3, GCS-alpha-1, Soluble guanylate cyclase large subunit, GUCY1A3, GUC1A3, GUCSA3, GUCY1A1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  7404351

• Physical Properties:

  Liquid