IGFBP4 Antibody

CAT: 0223-62-553Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-553Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
NCBI Gene ID
3487
Swiss Prot
P22692
Accession Number
P22692
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This IGFBP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human IGFBP4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
28 kDa
Fragment
Rabbit Ig
Symbol
IGFBP4
NCBI Official Name
Insulin-like growth factor-binding protein 4
NCBI Organism
Homo sapiens
Background Reference 01
Giroux, S., et al. Bone 47 (5) :975-981 (2010)
Background Reference 02
Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)
Background Reference 03
Bartling, B., et al. Int. J. Mol. Med. 25 (1) :89-96 (2010)
Background Reference 04
Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :
Other Product Names
Insulin-like growth factor-binding protein 4, IBP-4, IGF-binding protein 4, IGFBP-4, IGFBP4, IBP4
Tested Applications
WB, IHC-P
Protein ID
124065
Physical Properties
Liquid

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