ARPC1A Antibody

• Background:

  ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.

• NCBI Gene ID:

  10552

• Swiss Prot:

  Q92747

• Accession Number:

  Q92747

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ARPC1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the C-terminal region of human ARPC1A.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ARPC1A

• NCBI Official Name:

  Actin-related protein 2/3 complex subunit 1A

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Laurila, E., Genes Chromosomes Cancer 48 (4), 330-339 (2009)

• Background Reference 02:

  Machesky, L.M., Biochem. J. 328 (PT 1), 105-112 (1997)

• Other Product Names:

  Actin-related protein 2/3 complex subunit 1A, SOP2-like protein, ARPC1A, SOP2L

• Tested Applications:

  WB, IHC-P, IF, Flow

• Protein ID:

  88984001

• Physical Properties:

  Liquid