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WNT5A Antibody

CAT: 0223-62-006Size: 200 µLDry Ice: NoHazardous: No
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CAT#:0223-62-006Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. [provided by RefSeq].
NCBI Gene ID
7474
Swiss Prot
P41221
Accession Number
P41221
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This WNT5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human WNT5A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rabbit
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Symbol
WNT5A
NCBI Official Name
Protein Wnt-5a
NCBI Organism
Homo sapiens
Background Reference 01
He, X., et al. Science 275 (5306) :1652-1654 (1997)
Background Reference 02
Danielson, K.G., et al. J. Biol. Chem. 270 (52) :31225-31234 (1995)
Background Reference 03
Smolich, B.D., et al. Mol. Biol. Cell 4 (12) :1267-1275 (1993)
Background Reference 04
Clark, C.C., et al. Genomics 18 (2) :249-260 (1993)
Other Product Names
Protein Wnt-5a, WNT5A
Tested Applications
WB, IHC-P, Flow
Protein ID
212276478
Physical Properties
Liquid

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