TSPAN7 Antibody

• Background:

  TSPAN7 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and may have a role in the control of neurite outgrowth. It is known to complex with integrins. This gene is associated with X-linked mental retardation and neuropsychiatric diseases such as Huntington's chorea, fragile X syndrome and myotonic dystrophy.

• NCBI Gene ID:

  7102

• Swiss Prot:

  P41732

• Accession Number:

  P41732

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This TSPAN7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-124 amino acids from the Central region of human TSPAN7.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  28 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TSPAN7

• NCBI Official Name:

  Tetraspanin-7

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Radhakrishnan, Y., et al. Biol. Reprod. 81 (4) :647-656 (2009)

• Background Reference 02:

  Guilmatre, A., et al. Arch. Gen. Psychiatry 66 (9) :947-956 (2009)

• Background Reference 03:

  Noor, A., et al. Psychiatr. Genet. 19 (3) :154-155 (2009)

• Other Product Names:

  Tetraspanin-7, Tspan-7, Cell surface glycoprotein A15, Membrane component chromosome X surface marker 1, T-cell acute lymphoblastic leukemia-associated antigen 1, TALLA-1, Transmembrane 4 superfamily member 2, CD231, TSPAN7, A15, DXS1692E, MXS1, TM4SF2

• Tested Applications:

  WB, Flow

• Protein ID:

  17380550

• Physical Properties:

  Liquid