TXNDC12 Antibody

• Background:

  TXNDC12 belongs to the thioredoxin superfamily (see TXN; MIM 187700) . Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors

• NCBI Gene ID:

  51060

• Swiss Prot:

  O95881

• Accession Number:

  O95881

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This TXNDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the C-terminal region of human TXNDC12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  19 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  TXNDC12

• NCBI Official Name:

  Thioredoxin domain-containing protein 12

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Jessop, C.E., et al. J. Cell. Sci. 122 (PT 23), 4287-4295 (2009)

• Background Reference 02:

  Rowe, M.L., et al. Biochemistry 48 (21) :4596-4606 (2009)

• Background Reference 03:

  Jeong, W., et al. J. Biol. Chem. 283 (37) :25557-25566 (2008)

• Other Product Names:

  Thioredoxin domain-containing protein 12, Endoplasmic reticulum resident protein 18, ER protein 18, ERp18, Endoplasmic reticulum resident protein 19, ER protein 19, ERp19, Thioredoxin-like protein p19, hTLP19, TXNDC12, TLP19

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid